Artigos Científicos

Global Real-world Experiences With Pembrolizumab In Advanced Urothelial Carcinoma After Platinum-based Chemotherapy: The Aron-2 Study


Published: 18 Apr 2024 in Cancer Immunol Immunother

Keywords: ARON-2 study, Pembrolizumab, Real-world data, Survival, Tumor response, Urothelial cancer.

Changes in the Perioperative Management and Outcomes of Patients With Upper Tract Urothelial Carcinoma Undergoing Radical Nephroureterectomy at Memorial Sloan Kettering Cancer Center: Over 20 Years of Experience


Published: 1 Mar 2024 in American Urological Association Education and Research

Keywords: neoadjuvant, chemotherapy, outcomes, surgery, urothelial carcinoma, upper tract urothelial carcinoma

Use of concomitant proton pump inhibitors, statins or metformin in patients treated with pembrolizumab for metastatic urothelial carcinoma: data from the ARON-2 retrospective study



Published: 07 September 2023 in Medical Oncology

Keywords:  Urothelial cancer; Proton pump inhibitors; Statins; Metformin; ARON-2 study; Immunotherapy.

Prognostic factors in Latin American patients with localized and advanced renal cell carcinoma: a literature review

Published: 30 September 2023 in Medical Oncology

Keywords: Prognostic factors; survival predictors; renal cell carcinoma (RCC); Latin America (LA).

Association of human papillomavirus (HPV), p16, p53 and p63 expression with non-bilharzia-associated squamous cell carcinoma of the bladder and algorithm construction for histopathological grading prediction


Published: 19 April 2023 in Einstein (São Paulo)

Keywords:  Algorithms; Urinary bladder neoplasms; Human papillomavirus 16; Human papillomavirus type 53; Human papillomavirus 63; Papillomaviridae; Papillomavirus infections; Machine learning; Carcinoma; squamous cell.

Prognostic Factors in De Novo Metastatic Renal Cell Carcinoma: A Report From the Latin American Renal Cancer Group


Published: 01 December 2021 in JCO Global Oncology

Objective:  Are prognostic factors in de novo metastatic renal cell cancer different in Latin American population than those reported in other international cohorts?

Treatment of Localized and Locally Advanced, High-Risk Prostate Cancer: A Report From the First Prostate Cancer Consensus Conference for Developing Countries


Published: 01 December 2021 in JCO Global Oncology

Objective:  Generate a consensus on critical issues relevant to treatment of localized and locally advanced, high-risk prostate cancer (PCa) focusing on developing countries.

Functional and Oncological Outcomes of Renal Surgery for Hilar Tumors: Informing the Decisions in Risk-Adapted Management


Published: 28 July 2021 in Urology

Objective:  To describe the safety and efficacy of partial nephrectomy (PN) in comparison to radical nephrectomy (RN) for surgically managed renal hilar tumors.

Developments in Vascular-Targeted Photodynamic Therapy for Urologic Malignancies


Published: 19 November 2020 in Molecules

Keywords:  Vascular-targeted photodynamic therapy; Prostate cancer; Urothelial cancer.

Small renal masses in Latin-American population: characteristics and prognostic factors for survival, recurrence and metastasis – a multi-institutional study from LARCG database


Published: 02 July 2020 in BMC Urology


Keywords:  Kidney cancer; Nephron-sparing surgery; Latin America; Renal cell carcinoma; Nephrectomy.

Renal cell cancer treatment: an expert panel recommendation from the Latin American cooperative group-genitourinary and the Latin American renal cancer group: focus on surgery.


Published: 01 January 2019 in Therapeutic Advances in Urology


Background:  Renal cell cancer (RCC) is one of the 10 most common cancers in the world, and its incidence is increasing, whereas mortality is declining only in developed countries. Therefore, two collaborative groups, The Latin American Oncology Cooperative Group-Genitourinary Section (LACOG-GU) and the Latin American Renal Cancer Group (LARCG), held a consensus meeting to develop this guideline.

Optimizing the treatment of metastatic castration-resistant prostate cancer: a Latin America perspective


Published: 19 March 2018 in Medical Oncology


Keywords:  Chemotherapy; Hormonal therapy; Radium-223; Latin America; mCRPC.

Nephrometry scores and perioperative outcomes following robotic partial nephrectomy


Published: 01 December 2017 in International braz j urol


Keywords:  Kidney Neoplasms; Nephrectomy; Robotics.

First brazilian consensus of advanced prostate cancer: recommendations for clinical practice


Published: 01 June 2017 in International braz j urol


Keywords:  Prostatic Neoplasms; Practice Guideline [Publication Type]; Diagnosis

Mp16-17 Outcomes In Over 4,000 Patients With Renal Cell Carcinoma From The Latin American Renal Cancer Group (Larcg): A Focus On Metastatic Disease


Published: 01 April 2017 in Journal of Urology


Objective:  Over the past several years, a major international study collaboration has occurred among centers of excellence caring for kidney cancer termed the Latin American Renal Cancer Group (LARCG). The aim of the present study is to assess the impact of clinical and pathologic variables on cancer specific survival (CSS) and overall survival (OS).

Expression of PCA3 and PSA genes as a biomarker for differential diagnosis of nodular hyperplasia and prostate cancer


Published: 01 January 2015 in Genetics and Molecular Research


Keywords:  Prostate cancer; Nodular hyperplasia; PCA3; PSA; Gene expression.

MP10-16 18F-FDG Pet/CT As A Predictor Of Invasiveness In Penile Cancer Patients: Correlation With Pathology


Published: 01 April 2014 in Journal of Urology


Objective:  This study aimed to evaluate the status of the inguinal lymph nodes, the main prognostic factor in invasive squamous cell carcinoma of the penis, with picture 18F-FDG PET / CT.

Association between Literacy, Compliance with Prostate Cancer Screening, and Cancer Aggressiveness: Results from a Brazilian Screening Study


Published: 01 June 2013 in International braz j urol


Keywords:  Prostatic Neoplasms; Health Literacy; Mass Screening; Diagnosis.

Cutaneous ureterostomy with definitive ureteral stent as urinary diversion option in unfit patients after radical cystectomy


Published: 01 January 2013 in Acta Cirurgica Brasileira


Keywords:  Posoperative Complication; Survival; ASA Score; Morbidity; Aged; Bladder Cancer Neoplasms.

Lack of association between the ICIQ-SF questionnaire and the urodynamic diagnosis in men with post radical prostatectomy incontinence


Published: 01 January 2013 in Acta Cirurgica Brasileira


Keywords:  Urinary Incontinence; Prostatectomy; Urodynamic Questionnaires; Quality of Life.

Alternative techniques to reduce warm ischemia time in laparoscopic partial nephrectomy.


Published: 01 January 2013 in International braz j urol


Keywords:  Warm ischemia time reduction; Laparoscopic partial nephrectomy; Intermediate complexity renal tumors; Renal nephrometry; Renal tumor; Unclamping; Parenchymal suturing.

Use of low free to total PSA ratio in prostate cancer screening: detection rates, clinical and pathological findings in Brazilian men with serum PSA levels <4.0 ng/mL


Published: 14 August 2012 in BJU International


Objective:   To evaluate the role of the free to total prostate-specific antigen ratio (%fPSA) in identifying prostate cancer (PCa) in men with a prostate-specific antigen (PSA) level of 2.5–3.9 ng/mL and a normal digital rectal examination (DRE).

Sex with Animals (SWA): Behavioral Characteristics and Possible Association with Penile Cancer. A Multicenter Study


Published: 01 July 2012 in The Journal of Sexual Medicine


Keywords: Sex with Animals; Bestiality; Penile Cancer; Zoophilia; Risk Factor; Sexually Transmitted Diseases; HPV.

2037 Association Between Literacy, Cancer Agressiveness, And Adherence In Screened Men For Prostate Cancer: Results From A Brazilian Opportunistic Screening Study In 17,571 Men

Published: 30 April 2011 in Journal of Urology


Objective: Prostrate Cancer (PCa) screening remains controversial as its outcomes in reducing PCa deaths are not yet widely demonstrated and accepted. Little is known about the screened population literacy. This study aims to assess the association between the population literacy level and adherence and findings to PCa screening, and surgical pathological features.

Extending the indications and anatomical limits of pelvic lymph node dissection for prostate cancer: improved staging or increased morbidity?


Published: 24 December 2010 in BJU International


Objective:  To assess, in a risk/benefit analysis, the additional risk for complications and benefits of extending the indications and anatomical limits of pelvic lymph node dissection (plnd).

Role of Short-Term Antibiotic Therapy at the Moment of Catheter Removal after Laparoscopic Radical Prostatectomy


Published: 20 November 2010 in Urologia Internationalis


Keywords: Antibiotic prophylaxis; Laparoscopic radical prostatectomy; Catheter-related infection; Urinary tract infection.

Recovery of Renal Function After Open and Laparoscopic Partial Nephrectomy


Published: 31 October 2010 in European Urology


Keywords:  Laparoscopic Partial Nephrectomy (LPN); Open Partial Nephrectomy (OPN); Renal Function; Glomerular Filtration Rate (GFR); Renal Disease; Renal Tumor; ASA Score;

Extended Pelvic Lymph Node Dissection in Robotic-assisted Radical Prostatectomy: Surgical Technique and Initial Experience


Published: 31 May 2010 in Urology


Objective: To describe, and show in the accompanying video segments, a technique for extended pelvic lymph node dissection (ePLND) in robotic-assisted radical prostatectomy (RARP) and report our clinicopathologic and perioperative outcomes. The extent of pelvic lymphadenectomy during radical prostatectomy has not been standardized. However, evidence demonstrates that an ePLND yields a greater number of positive nodes.

V475 Modification Of Apical Dissection Technique In Laparoscopic Radical Prostatectomy


Published: 30 April 2010 in Journal of Urology


Objective: To assess the impact of a modified technique of apical dissection during Laparoscopic Radical Prostatectomy on continence outcomes.

Comprehensive Standardized Report of Complications of Retropubic and Laparoscopic Radical Prostatectomy


Published: 31 March 2010 in European Urology


Objective: To define comprehensively the incidence, severity, and timing of onset of medical and surgical complications of open retropubic prostatectomy (RP) and laparoscopic radical prostatectomy (LP) using a standardized reporting methodology to facilitate comparison.

Other biomarkers for detecting prostate cancer


Published: 01 January 2010 in BJU International


Keywords: Prostate-specific antigen (PSA); human kallikrein 2; urokinase-type plasminogen activator receptor; prostate-specific membrane antigen; early prostate cancer antigen; PCA3, α-methylacyl-CoA racemase and glutathione S-transferase π hypermethylation.

Critical Evaluation of Perioperative Complications in Laparoscopic Partial Nephrectomy


Published: 07 December 2009 in Urology


Objective:  To analyze our experience with laparoscopic partial nephrectomy (LPN) to detail postoperative adverse events and identify factors that may contribute to adverse surgical outcomes. Complications from LPN result from a variety of factors, both technical and inherent.

UP-1.074: Zoophilia Characteristics and Association with Penile Cancer: Initial Results of a Multicentric Brazilian Case-Control Study


Published: 31 October 2009 in Urology


Keywords: Penile carcinoma (PC); Unfavorable hygiene; Socioeconomic conditions; Phimosis; Chronic Balanitis; Premalignant lesions; Tobacco exposure; Promiscuity; HPV infection; Brazilian multicentric case-control study; Zoophilia (ZP).

Extended Pelvic Lymph Node Dissection in Robotic-assisted Radical Prostatectomy: Surgical Technique and Initial Experience


Published: 31 May 2010 in Urology


Keywords: Extended Pelvic Lymph Node Dissection (ePLND); Robotic-assisted Radical Prostatectomy (RARP); Clinicopathology, Perioperative Outcome.

Prostatic specific antigen for prostate cancer detection


Published: 01 October 2009 in International braz j urol


Keywords:  Prostate-specific antigen (PSA); Prostate Cancer (PC); Diagnosis; Prostate-specific Antigen; Biopsy.

Tumor Size is Associated With Malignant Potential in Renal Cell Carcinoma Cases


Published: 31 May 2009 in Journal of Urology


Keywords: Malignant Carcinoma; Renal Cell Carcinoma; Renal Cortical Tumors; Malignant Histology; Nuclear grade; Logistic Regression Analysis;

Critical Evaluation Of Complications In Laparoscopic Partial Nephrectomy


Published: 01 April 2009 in Journal of Urology


Keywords:  Nephron-sparing Surgery (NSS); T1a Tumors; Laparoscopic Partial Nephrectomy (LPN); Minimally Invasive Surgery; Risk factors;

Extend Pelvic Lymph Node Dissection In Robotic Assisted Laparoscopic Radical Prostatectomy


Published: 01 April 2009 in Journal of Urology


Keywords:  Lymph Node; Pelvic; Robotic Laparoscopy; Radical Prostatectomy (RP); Robot-assisted Laparoscopic Prostatectomy (RALP);

518 Laparoscopic Pelvic Lymphadenectomy For Clinically Localized Prostate Cancer: A Risk Vs. Benefit Analysis


Published: 31 March 2009 in European Urology Supplements


Keywords:  Laparoscopy; Pelvic Lymphadenectomy; Prostate Cancer;

Comparison of gelatine matrix-thrombin sealants used during laparoscopic partial nephrectomy


Published: 01 December 2008 in BJU International


Objective:  To compare haemostasis and other outcomes after the use of bovine-derived or porcine-derived gelatine matrix-thrombin sealants (GMTS) in a continuous series of patients during and for 6 months after laparoscopic partial nephrectomy (LPN).

Surgical Outcomes In Candidate Patients For Active Surveillance Or Focal Therapy: The Inaccuracy Of Diagnostic Template Biopsy


Published: 01 April 2008 in Journal of Urology


Keywords: Prostate Cancer; PCA; Active Surveilance (AS); Indolent Tumors; Focal Treatment (FT); Radical Prostatectomy (RP);